Parkinson's disease is a neurological disorder that affects the brain and central nervous system. It can affect movement, speech, and other functions. The brain cells that produce dopamine, a chemical that helps control movement, die off over time in people with Parkinson's disease. This can lead to problems with movement and coordination as well as cognitive issues, such as difficulty in thinking, paying attention and memory problems. There is no cure for Parkinson's disease, but there are ways that can help improve symptoms, including regular exercise. Learn more.